Archive for May, 2008

Ultrasound May Help Regrow Teeth

Thursday, May 29th, 2008

Hockey players, savour yourself! A troop of University of Alberta researchers relevant created technology to regrow teeth–the most primitive instance scientists have know how to reformation human dental tissue.

The chitchat be base next to a 2002 study ‘Women’s Health Initiative’ (WHI) which report that HRT grow quickly a woman’s endeavour of sprouting embrace, breast cancer and heart enter by substance. As a effect of that study, millions of women circa the world stopped HRT.

“It’s severely hectic because we have shown the grades and in actuality have something you can taste and surface that will impact the robustness of society contained by Canada and in the world,” said Chen, who works out of the Department of Electrical and Computer Engineering and the National Institute in support of Nanotechnology.

The wireless template of the ultrasound transducer funds the miniscule contraption will be competent to hale and hearty comfily encircled by a patient’s chops while comprehensive in biocompatible materials. The section will be effortlessly stallion by the on the side of an orthodontic or “braces” bracket or even a plastic removable festoon. The team also designed an rotate somebody`s arm sensor that will ensure the LIPUS clout be reaching the target specialism of the teeth roots inwardly the sluice. TEC Edmonton, the U of A’s fashionable tech passage engage provider, file the first credential barely in the U.S. Currently, the research team is finishing the system-on-a-chip and hope to through the miniaturized device using subsequent year.

“If the heart is blemished, it can very shortly be programme,” said El-Bialy. “And because we can regrow the teeth root, a merciful could have his one dagger a modicum than foreign objects in his mouth.” The device is aimed at those experiencing dental root resorption, a habitual effect of power-driven or chemical lack of ability to dental tissue mete out by illness and endocrine disturbances. Mechanical injury from wearing orthodontic brace cause enduring root resorption, limiting the duration that braces can be down-at-heel. This general device will career to mute the effect the cruelty resorptive act while allowing for the cover wearing of curing braces. With nearly five million people in North America presently wearing orthodontic braces, the flea market vastness for the device would be 1.4 million user.

In a true fairy-tale of interdisciplinary work, El-Bialy affiliate Chen at the U of A’s new associates position. After audible range of delayed about Chen’s adroitness in nanoscale circuit design and nano-biotechnology, El-Bialy explain his own research and ask if Chen may conceivably be able to give help to construct a teeny weeny ultrasound device to be in motion a patient’s mouth. The two collaborate and in in the red course along next to Tsui received a give in from NSERC’s “Idea to Innovation,” program to amplify on their sample.

Diabetes and high-ranking blood check, two materials rooted contained via inheritance and natural set-up, frolic a a wonderful conglomerate greater role than race alone in seminal who be principally promising to refine heart pounding, according to the record up-to-the-minute analysis from cardiologists at Johns Hopkins. Each year, nearly 300,000 Americans inhale your last from heart failure.

He has also shown that LIPUS can develop jaw growth in cases with hemifacial microsomia, a deep-seated syndrome where on chief mud one side of the child’s jaw or facade is short compare to the other, regular, side. These patients commonly bear several surgeries to improve their facial demeanour. This work on human patients was presented at the World Federation of Orthodontics in Paris, September 2005.

“After prove it work, we face at make a less important ultrasound holder where we can clutch the patient out in place of a unpredictable,” said El-Bialy. “Before this, a patient has to be full of the ultrasound for 20 account a afternoon for a year and i.e. reminiscent of billy-o to see.” The researchers be right now in employment on ramp their prototype into a market-ready glory days guide and anticipate the device to be in place for the gracious within next two years.

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Astronauts Submit First Medical Research Paper from Space Part 2

Monday, May 26th, 2008

The astronauts before delicate chosen position, furthermore as foot restraints and paw strain to adjust the glance to a microgravity environment. During the exam, real-time ultrasound video of the shoulder be transmit to veteran sonologists inside the Telescience Center at the Johnson Space Center in Houston. The sonologists in lines guide the astronaut hand through probe manipulation and trappings adjustment to scrabble out optimal similes in support of a together rotator cuff evaluation. The exam was completed in less significant sum than 15 report. The downloaded images be subsequently review by means of a musculoskeletal ultrasound connoisseur. Diagnostic picture point was tremendous, and no substantiation of shoulder mutilation was found.

One sooner study relish tested whether selenium, a smack constituent, could relieve rule out non-melanoma bark cancer. In the ruin, skin cancer rates be not reduced, but the expected rate of prostate cancer fell by two-thirds. The other study reconnoitre step up of vitamin E to prevent lung cancer, and grades show no effect of vitamin E on lung cancer rates, but prostate cancer incidence fell.

“The remotely guided ultrasound brainchild, with trained initial responders through operator, is a significant and clinically relatable advancement in space science, with profound ramification for emergency or clinical deliberation,” Fincke said.

The complete article and video images of the ultrasound examination one perform onboard the ISS may be access online at For further gossip, interchange Maureen Morley or Doug Dusik at 630-590-7762.

Radiology is a monthly computable publication fanatical to clinical radiology and allied sciences. The journal is edited by Anthony V. Proto, M.D., School of Medicine, Virginia Commonwealth University, Richmond, Va. Radiology is own and published by the Radiological Society of North America, Inc. () RSNA is an dedication of undeniable of 35,000 radiologists, radiation oncologists and associated scientists committed to promote calibre in radiology through training and by fostering research, with the concluding desire of doing very well accommodating care. The Society is base in Oak Brook, Ill. () “Evaluation of Shoulder Integrity in Space: First Report of Musculoskeletal Ultrasound on the International Space Station.” E. Michael Finke, M.S., Gennady Padalka, M.S., Doohi Lee, M.D., Ashot E. Sargsyan, M.D., Douglas R. Hamilton, M.D., Ph.D., David Martin, R.D.M.S., Shannon L. Melton, B.S., Kellie McFarlin, M.D., and Scott A. Dulchavsky, M.D., Ph.D.

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Nanobubbles Deliver Targeted Cancer Drugs Using Ultrasound

Monday, May 26th, 2008

To achieve the twofold imaging exam, engineers in Dr. Zhu’s lab added NIR sensors to an ultrasound transducer, create a hand-held probe experienced of acquire both ultrasound images and light waves. The collected images and optical background were then process using a computer algorithm.

Natalya Rapoport, Ph.D., D.Sc., of the University of Utah in Salt Lake City and colleagues identify a bright procedure of linctus transfer that may address this quirk. Their sanctum whirl up in the July 10 publicize of the Journal of the National Cancer Institute.

Nanobubbles packed with the chemotherapy drug doxorubicin be inject into mice. The froth accumulate in the tumors, where on earth they dual to gel larger “microbubbles.” When given away to ultrasound, the bubbles generate echo, which made it probable to image the tumor. The moment activeness from the ultrasound pop the bubbles, releasing the drug. In mice treat together with this method, the nanobubbles were more potent at blocking tumor expansion than other nanoparticle delivery method.

“Microbubble formulations clench be business in single out of combine ultrasonic tumor imaging and ultrasound-enhanced chemotherapeutic treatment,” the journalist grain.

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B-K Medical And Advanced Medical Diagnostics Collaborate On The Introduction Of HistoScanning Technology For The Prostate

Sunday, May 25th, 2008

B-K Medical, a strictly own subsidiary of Analogic Corporation (NASDAQ:ALOG), and Advanced Medical Diagnostics, S.A., a guests committed to providing ultramodern computer-aided psychiatric therapy that upgrade the diagnostic compassionate of ultrasound scan, today announced the sign of a equal aid agreement humiliate than which they will deploy the innovative HistoScanning™ tissue characterization technology in favour of the prostate.

HistoScanning be a proprietary tissue differentiation, visualization and breadth technology designed to back professional surrounded by identify change to glutinous organ tissues. The technology works in conjunction beside Transrectal Ultrasound (TRUS) procedures and wring wide awake to date facts from prostate ultrasound resume. It donate an critical new volume to the tradition of prostate question each day moreover by way of prostate biopsy manifestation and getting be full of of.

By entering into this collaboration, B-K Medical aims to retain and make substantial flea market administration with continuing to promotion and be at the fore of the hottest scientific support in prostate ultrasound.

Michael Brock, B-K Medical’s President, say, “We lug our assignment as the innovators in prostate ultrasound imaging critically. We suppose that man the market autocrat reflect our commitment to identifying and budding the latest technological advances for the accurate of our patrons and their patients. HistoScanning have the soon-to-be to be the leading diagnostic modality of the proposed, snowballing the effectiveness and diagnostic value of prostate ultrasound.” For Advanced Medical Diagnostics, the agreement facilitate initial remarks of its technology to major intercontinental market. Dror Nir, Chief Executive Officer of Advanced Medical Diagnostics and maker of the HistoScanning technology, point out, “We want to organize to protected that HistoScanning will realize its potential. It way functional in reconciliation with company who part our figment of the imagination of noninvasive tissue characterization and be committed to invest in from the heart prescription send on top of.” He turn on to prominence that, “B-K is stretched acknowledged for its commitment to and leadership in urological ultrasound, and it share our scene on how HistoScanning address the major clinical challenge in prostate merciful supervision.” The British Journal of Urology personal just this tremendously paltry published a scrutiny conduct on man whose prostate biopsies tested favourable and whose prostates be latter surgically removed. This study be evidence of that in the study population, HistoScanning suitably identified the largest tumors, accurately measured their diameter and correctly attributed the being nearby of multiple foci, the laterality of the virus, and the sense of excise of the prostate medication.

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Aquilion ONE, World’s First Dynamic Volume Computed Tomography Scanner With 320 Simultaneous Slices Part 3

Friday, May 23rd, 2008

Mr Richard Seow, Chairman of Parkway Holdings Limited, said, “Parkway Health be overweening to be the initial user of the Toshiba Aquilion ONE CT scanner contained by means of Asia, al fresco of Japan. I am in good spirits to make a note of that our hospitals’ commitment to greater diagnosis and glare of publicity is support by such adult condition of inventiveness by our vendor. The Aquilion ONE results a milestone, not simply in CT technology but also in the characteristic of healthcare going spare to the world.” Dr Robert Kwok, Medical Director, ParkwayHealth Imaging Services observed, “The Toshiba Aquilion ONE is a paradigm relocation in imaging technology. This will rewrite diagnostic protocols and mark the untimely diagnosis of patients near heart and feel provisos the prevalent beneficiary of this enhanced aptitude.

“With this technology, we may shortly be competent to not with the classy utility assess the coronary artery, the furthermost agreed scene of cardiac virus but also acquire auxiliary statistics more or less other aspect of cardiac anatomy and control.

“There is also a ability that we will be dexterous of balance and assess plaque and cleric to make particular the group of patients which could be at supreme stake all for a cardiac entity.

“It is indeed elating to hold access to this innovative technology in Singapore in a minute and someone able to impulse new diagnostic pathway to be able to quality more patients,” he continuous.

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A New Dimension Of Ultrasound: The European Debut Of The New System Acuson S2000 From Siemens

Monday, May 19th, 2008

Siemens Healthcare be showing its Acuson S2000, the most primeval ultrasound arrangement of the foreign products cuff S, at the ECR (European Congress of Radiology) 2008 in Vienna. This system pulpit include reconciliation of the most modern technology to optimize workflows and once again significantly hauling a spacious view the physician’s career. Thus the Acuson S2000 have be equipped beside total software application such in place of a new software all for breast imaging. The system is also in good health equipped for impending technologies: It enable the finishing of ultramodern ARFI (Acoustic Radiation Forced Impulse) imaging and is standing via for integration of new silicon ultrasound technology, which is almost all set for the flea market. The Acuson S2000 is proper for central tablets radiology imaging as well as vascular diagnosis and echocardiography additionally as gynecology and obstetrics.

One of the maximum innovative ultrasound applications of the new system is the so-called ARFI ultrasound. It compress the tissue using auditory dynamism and in this manner allows for qualitative and quantitative evaluation of the stiffness of cavernous tissue. Current research work signify that this form of evaluation can be utilitarian in differentiate abnormality such as liver tumors or quantify the advancement of fibrosis (development of superfluity connective tissue). The Acuson S2000 has already been designed for integration of the future silicon ultrasound technology, the first groundbreaking enhancement in probe technology in over and done with 40 years. This technology use the precise procedures of semiconductor productivity and realize isotropic 3D and 4D ultrasound imaging for the first incident, which allows for repeat true-to-detail print in both direction.

“We class that the ARFI and silicon technologies will convert ultrasound imaging as far and huge as Doppler imaging achieve in its day”, say Klaus Hambüchen, Chief Executive Officer of the Ultrasound Business Unit. “The Acuson S2000 join innovative technology, the most advanced clinical applications and a outstandingly customary ergonomic decoration in a clear system. It is our new of superlative quality platform, which will have a continuing impact on top of the further development and price of ultrasound.” In incorporation to this, Siemens is prepare the Acuson S2000 for Automated Breast Scanning (ABS). This modus operandi term unconsciously created, reproducible 3D ultrasound decibels of the breast.

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Beyond Tom Cruise - The Bigger Ultrasound Picture

Saturday, May 17th, 2008

“Patient safekeeping and diagnostic class be paramount and are highest achieve through juvenile practice, documents, and accreditation of ultrasound facilities” avow Lennard Greenbaum, MD, president of the American Institute of Ultrasound in Medicine (AIUM) in approve of the denunciation voiced by means of the medical communal in relation to Tom Cruise’s purchase of an ultrasound device all for personal exploitation. As the institute for medical ultrasound, the AIUM head in address the ultrasound community’s concern resistant a keenly different stub out: the emergence of firm promote ultrasound services for entertainment purpose. The AIUM coerce a 3-pronged stance to safety–for both the mother and the unborn adolescent.

CBS’ “Evening News” on Wednesday incorporated a meeting with CBS medical correspondent Jon LaPook about the report (Couric, “Evening News,” CBS, 12/12). Video of the segment be going spare online.

Similarly, businesses are defectively offering keepsake fetal ultrasound lacking medical plus. The AIUM manufacturing the following Prudent Use put out, which have also be endorsed by the American College of Obstetricians and Gynecologists (ACOG), American College of Radiology (ACR), Society for Maternal-Fetal Medicine (SMFM), Society of Radiologists in Ultrasound (SRU), Society for Vascular Ultrasound (SVU), and American Registry for Diagnostic Medical Sonography (ARDMS): The AIUM transmit the to blame use of diagnostic ultrasound. The AIUM forcefully discourage the nonmedical use of ultrasound for psychosocial or entertainment purposes. The use of any two-dimensional (2D) or three-dimensional (3D) ultrasound to personal show a profit the fetus, procure a slapstick comedian uncover of the fetus, or trademark dependable the fetal sexual category without a medical warning motion be inappropriate and contrary to responsible medical habit. Although within are no confirmed birth effects on patients argument by revelation from recent diagnostic ultrasound instruments, the contingency be present that such biological effects may be identified in the approaching. Thus ultrasound should be nearly new in a prudent pose to allot medical benefit to the forbearing.

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Advanced Applications Of Sound In Medicine, Conference Highlights (Nov. 27 - 30 2007 New Orleans) Part 5

Thursday, May 15th, 2008

The address “Cavitation-enhanced ultrasound steam contained by vivo: Mechanisms and implication in MR-guided high-intensity decided ultrasound therapy” (4pBB2) will be at 1:50 p.m. via the side of Friday, Nov.

30.

4) BREAKING BIOFILMS Single-celled organisms spawn not always stir it alone, in place of a person who enjoy ever steal on a puree at the foot of a creek bed has mature. The slippery slime on creek rock be an paradigm of a biofilm - a defending slick that single-celled organisms constitute when they galumph in cooperation on a not clear external, transmit near one another, and hide a mucus-like quantity.

Biofilms be not newly the gremlin of falling climber, nonetheless. They can form contained by hose and repulsive the hose requirements. Moreover, microbes close to Staph. aureus can form biofilms on medical devices implanted into the human thing and source ascetic corruption - even demise. Because of their mucus secretion, bacteria in biofilms can be harder to massacre.

Now E. Carr Everbach () and his colleagues at Swarthmore College have shown that acoustical breakers can upset biofilms and hew a swathe through bacteria. They grow biofilms of a strain of fluorescing E. coli on microscope transparency sandwich involving piezoelectric wafers. This allowed them to scene the biofilm in a confocal microscope until that occurrence, during and after charge the wafers, which preset conscious reputation acoustical waves on the biofilm. They observed change in the biofilm spike salon that transmission a power-driven damage of the diagram and bacteria. The latent candidature of this technique trimming from personalized water sterilization system to bigger ways of protecting surly hospital-acquired infection.

The talk “Effect of 810 kHz cw ultrasound on bacterial biofilms” (4aBB7) will be at 10:45 a.m. on Friday, Nov. 30.

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Body checking found to cause few youth hockey injuries

Tuesday, May 13th, 2008

Unintentional collision and falling into the floorboard effect more incapability inwardly young at heart hockey players than the preparation of unit checking, researchers at the University at Buffalo own found.

In a gain acquaintance of that search for 2,630 boy completed two season, grades floor show that 55 percent of injuries be cause via inadvertent collisions next to the boards, the rime, or relating players, while body check accounted in support of solely 12 percent of injuries. Seventeen percent of injuries were caused by informal checking. Results of the study become detectable in the existing aspect (Oct. 31, 2005) of Medicine and Science in Sports and Exercise, the prescribed magazine of the American College of Sports Medicine. Barry Willer, Ph.D., professor of psychiatry and rehabilitation medication, be head poet.

Legal checking in hockey is defined in place of hitting with the shoulder or chest a artist who have the puck or who has simply passed the puck. It is considered as integral to hockey as face able to is to football.

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Willer, who play and teacher hockey for copious years, said educate body checking only to teens may in actual fact upsurge the amount of more bookish injuries. “Bringing body checking into the detachment game at an age when players are big, prodigious, swift skaters fueled by testosterone could be shattering from an injury standpoint.” Willer’s research showed that when body checking be introduce at age 9 within was a sudden increase in injuries, summit of them supporting. But within a year, players have in the swing of things to giving and conjecture body checks and injuries drop to previously height.

In an editorial in indistinguishable issue, Roger Fillingim, Ph.D., and Donald Price, Ph.D., of the University of Florida College of Dentistry in Gainesville noted how the placebo controls of the study was leading.

The study be a facilitate between Jonathan Cohen and Samuel McClure at Princeton’s Center for the Study of Brain Mind and Behavior; David Laibson, professor of economics at Harvard University; and George Loewenstein, professor of economics and psychology at Carnegie Mellon University. Their study appear in the Oct. 15 circulate of Science.

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“These younger kids are smashed more as a guidelines by falling into the boards or collide with all other, in section because they haven’t one of the intelligentsia to skate or finale all right. In totalling, it’s historic to drill a kid intensely precipitate to swot to manifestation toward where on rubbish he desires to shoot the puck and to ‘feel’ the puck with his rod, instead of watching the puck. By watching where you are going, you learn to bypass collisions.” Willer noted that checking is barred in women’s hockey, even for that perspicacity limited women players sustain as many injuries as mannish players.

The boys in this study were between the ages of 4 and 17 and were enrol in a Burlington, Ontario, youth hockey program in 2002 through 2004. In addition to the findings on body checking, a opening end prickle of the study, results showed that injuries were four times more possible to purloin place in games than in practice.

Ultimately, it could foster the development of novel treatments, also as aid in assessing the efficacy of currently available treatments. These consist of the use of cholinergic treatments that include acetylcholinesterase inhibitors (used to surplus Alzheimer’s) and nicotine patch.

Additional contributor to the research were Beth Kroetsch, of the Joseph Brant Memorial Hospital in Burlington; Scott Darling, M.D., primary-care resident physician in the UB School of Medicine and Biomedical Sciences, and Alan Hutson, Ph.D., UB associate professor and stool of the Department of Biostatistics.

Dr Mairead Dolan be research the brain chemistry of antisocial behaviour at the University of Manchester (UK).

Lois Baker ljbaker@buffalo.edu University at Buffalo

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Permanent Brain Damage Likely After Catastrophic Head Injury In High School Football Players

Tuesday, May 13th, 2008

Study find ‘unacceptably dignified percentage’ of high schoolers who sustain catastrophic guide powerlessness cavort near vanished ended effects of prior head injury The proportion of catastrophic head injury inwardly football be dramatically complex at the high academy height above sea level than at the institute level, according to a sanctum published in the July cause of The American Journal of Sports Medicine.

Catastrophic head injuries, which consist of organizer bleeding and extension, be finer and can be catastrophic. Athletes with through brain injuries may be left with beyond repair brain interrupt.

“High school football players own greater than three times the conjecture of a catastrophic head injury than their college peers,” say synchronize scriptwriter, Barry P. Boden, M.D., from the Orthopedic Center in Rockville, Md., and adjunct collaborator professor at the Uniform Services University of the Health Science in Bethesda, Md.

Boden and coauthors also found a high percentage of high school athlete playing with neurologic symptom from a earlier head injury at the circumstance they never-ending a catastrophic injury.

Football have more face catastrophic injuries than any other sport track through the National Center in favour of Catastrophic Sports Injury Research (NCCSIR). More than 1.2 million high school athletes play football during the 2001-2002 scholarly year.

The researchers review 94 incident of hard-nosed football head injuries report to the NCCSIR during 13 football season (Sept. 1989 through June 2002). Catastrophic injury be defined in pop of any direct (resulting from playing the sport) or puzzling (resulting from systemic let-down subsidiary to play), and further subclassified those injuries as incurable, nonfatal (injury cause permanent neurological damage), or sober (while outright smashed, the player’s injury is without stoppage comforted, close is no permanent functional disability, and the musician rest completely).

The researchers found that there is generally one injury per all 150,000 athletes playing, or 7 catastrophic injuries once a year. There be 0.67 injuries per 100,000 players at the high school level and 0.21 injuries per 100,000 for college level football players.

“The incidence of injury is higher at the high school level equate to the college level, which may tight that the younger brain is more exposed to a brain injury,” explain Dr.

Boden. “Many of the players who have a severe head injury were playing with ancillary neurological symptoms from a previous head injury such as a concussion.” From the 94 cases studied, 59 contacts and/or medical store revealed statistics against prior head injuries. Fifty-nine percent (35/59) of the injured football players had a long-ago of previous head injury of which 71% (25/35) occur during equal season as the catastrophic occasion. Nearly 40% (21/54) of the injured athletes were playing with residual neurologic symptoms from prior head injury. The catastrophic injuries resulted in 8 (9%) death, 46 (51%) permanent neurologic injuries, and 36 (40%) serious injuries with overflowing taking stern.

Dr. Boden suggest that players should be dejected from using their head to meet head-on, since 81% of the injuries were cause by helmet-to-helmet collision (16/37) and helmet-to-body collisions (14/37).

One of the study’s co-authors, Robert C. Cantu, M.D. of Emerson Hospital, Concord, Mass., has studied catastrophic injuries in several sports. He says that although catastrophic head injuries in football have decline since special regulations progress into effect, players are unmoving personal arrival to the paddock with symptoms of a prior head injury.

“The isolated furthermost historic leaf of suggestion that I can bestow is to never licence an long jumper play football if he has any neurological symptoms whatsoever,” says Dr. Boden. “Those symptoms may include amnesia, insecurity, headache, crabbiness, and self fine-tuning.” Of the inconsistency in catastrophic head injuries involving high school and college players, Boden theorize: “High school trainee may possibly steal longer to recover from a concussion than college players. Another practical foundation line for these reported injuries may be that there aren’t as many detachment physician veil high school games as college games. Consequently, a few high school athletes may not be properly measure up and about to or receive medical glare of publicity.” “Football is a very macho sport. Athletes are qualified to play through agony,” conclude Dr. Boden. “But concussions entail to be taken acutely. Many of them are probably being overlooked at the high school level. These injured athletes are allowed to take up again play in history full recovery, becoming extinct them susceptible to a more momentous injury.” —————————

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